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90
Millipore 5β cholanic acid (chola) ≥ 99
5β Cholanic Acid (Chola) ≥ 99, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Anatrace sodium cholate (3α,7α,12α-trihydroxy-5β-cholan-24-oic acid monosodium salt)
Sodium Cholate (3α,7α,12α Trihydroxy 5β Cholan 24 Oic Acid Monosodium Salt), supplied by Anatrace, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Valiant Co Ltd cholic acid
Cholic Acid, supplied by Valiant Co Ltd, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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steraloids inc cholate d4
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Cholate D4, supplied by steraloids inc, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millipore 3a, 7a,12a-trihydroxy-5b-cholanic acid sodium salt
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
3a, 7a,12a Trihydroxy 5b Cholanic Acid Sodium Salt, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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steraloids inc sodium cholate
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Sodium Cholate, supplied by steraloids inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Isotec Inc deuterated-cholate product #614149
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Deuterated Cholate Product #614149, supplied by Isotec Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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HepQuant LLC cholate cloral; cholate clearance po; hepquant-oral
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Cholate Cloral; Cholate Clearance Po; Hepquant Oral, supplied by HepQuant LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Millipore sodium cholate (na-cholate
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Sodium Cholate (Na Cholate, supplied by Millipore, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Sinopharm ltd deoxysodium cholate
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Deoxysodium Cholate, supplied by Sinopharm ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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HepQuant LLC oral cholate clearance cholate cloral
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Oral Cholate Clearance Cholate Cloral, supplied by HepQuant LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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HepQuant LLC hepquant-oral
Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for <t>12</t> weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.
Hepquant Oral, supplied by HepQuant LLC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Image Search Results


Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for 12 weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.

Journal: Scientific reports

Article Title: Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats.

doi: 10.1038/s41598-017-04536-5

Figure Lengend Snippet: Figure 2. Histological features of ANIT-induced cholestasis model. (A) H&E and Sirius red stained liver sections from normal group, 8w model group, 12w model group and YCHT-treated group. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for 12 weeks; YCHT-treated, ANIT- induced cholestasis rats treated with YCHT from 9th week to 12th week. Original magnifications × 100 for H&E, and × 200 for Sirius red. (B) Immunofluorescence analysis of CK19 in liver sections. (C) The positive area of CK19 in different groups. (D) Immunofluorescence analysis of Collagen I in liver sections. (E) The positive area of Collagen I in different groups. *P < 0.05; **P < 0.01; ***P < 0.001.

Article Snippet: 9Scientific RepoRts | 7: 4211 | DOI:10.1038/s41598-017-04536-5 taurodeoxycholate (TDCA), glycoursodeoxycholate (GUDCA), glycohyodeoxycholate (GHDCA), glycochenodeoxycholate (GCDCA), glycodeoxycholate (GDCA), cholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol-2,2,4,4-d4, CA-d4), glycocholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol N-(Carboxymethyl)-amide-2,2,4,4-d4, GCA-d4), lithocholate-d4 (5β-Cholanic acid-3α-ol-2,2,4,4-d4, LCA-d4), and deoxycholate-d4 (5β-Cholanic acid-3α, 12α-diol-2,2,4,4-d4, DCA-d4) were purchased from Steraloids Inc. (Newport, RI).

Techniques: Staining, Immunofluorescence

Figure 3. mRNA expression of IL-6, IL-10, TGF-β1, IL-17A, IL-17F, and α-SMA in the liver. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for 12 weeks; Yinchenhaotang- treated, ANIT-induced cholestasis rats treated with Yinchenhaotang from 9th week to 12th week. All data are presented as mean ± SEM. (n = 8–12; *P < 0.05; **P < 0.01).

Journal: Scientific reports

Article Title: Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats.

doi: 10.1038/s41598-017-04536-5

Figure Lengend Snippet: Figure 3. mRNA expression of IL-6, IL-10, TGF-β1, IL-17A, IL-17F, and α-SMA in the liver. Normal, healthy rats; 8w Model, ANIT treatment for 8 weeks; 12w Model, ANIT treatment for 12 weeks; Yinchenhaotang- treated, ANIT-induced cholestasis rats treated with Yinchenhaotang from 9th week to 12th week. All data are presented as mean ± SEM. (n = 8–12; *P < 0.05; **P < 0.01).

Article Snippet: 9Scientific RepoRts | 7: 4211 | DOI:10.1038/s41598-017-04536-5 taurodeoxycholate (TDCA), glycoursodeoxycholate (GUDCA), glycohyodeoxycholate (GHDCA), glycochenodeoxycholate (GCDCA), glycodeoxycholate (GDCA), cholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol-2,2,4,4-d4, CA-d4), glycocholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol N-(Carboxymethyl)-amide-2,2,4,4-d4, GCA-d4), lithocholate-d4 (5β-Cholanic acid-3α-ol-2,2,4,4-d4, LCA-d4), and deoxycholate-d4 (5β-Cholanic acid-3α, 12α-diol-2,2,4,4-d4, DCA-d4) were purchased from Steraloids Inc. (Newport, RI).

Techniques: Expressing

Figure 5. The mRNA expression of liver FXR, CAR, VDR, TGR5, NTCP, BSEP, OATP1a1, MRP2, MRP3, and MRP4, and ileum ASBT. Normal, healthy rats; Model, ANIT treatment for 12 weeks; YCHT, ANIT-induced cholestasis rats treated with Yinchenhaotang from 9th week to 12th week. All data are presented as mean ± SEM. (n = 8–12; *P < 0.05; **P < 0.01).

Journal: Scientific reports

Article Title: Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats.

doi: 10.1038/s41598-017-04536-5

Figure Lengend Snippet: Figure 5. The mRNA expression of liver FXR, CAR, VDR, TGR5, NTCP, BSEP, OATP1a1, MRP2, MRP3, and MRP4, and ileum ASBT. Normal, healthy rats; Model, ANIT treatment for 12 weeks; YCHT, ANIT-induced cholestasis rats treated with Yinchenhaotang from 9th week to 12th week. All data are presented as mean ± SEM. (n = 8–12; *P < 0.05; **P < 0.01).

Article Snippet: 9Scientific RepoRts | 7: 4211 | DOI:10.1038/s41598-017-04536-5 taurodeoxycholate (TDCA), glycoursodeoxycholate (GUDCA), glycohyodeoxycholate (GHDCA), glycochenodeoxycholate (GCDCA), glycodeoxycholate (GDCA), cholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol-2,2,4,4-d4, CA-d4), glycocholate-d4 (5β-Cholanic acid-3α, 7α, 12α-triol N-(Carboxymethyl)-amide-2,2,4,4-d4, GCA-d4), lithocholate-d4 (5β-Cholanic acid-3α-ol-2,2,4,4-d4, LCA-d4), and deoxycholate-d4 (5β-Cholanic acid-3α, 12α-diol-2,2,4,4-d4, DCA-d4) were purchased from Steraloids Inc. (Newport, RI).

Techniques: Expressing